Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The NLRP3 Inflammasome and Its Role in the Pathogenicity of Leukemia

28 Jan 2021

Abstract excerpt

Chronic inflammation contributes to the development and progression of various tumors. Especially where the inflammation is mediated by cells of the innate immune system, the NLRP3 inflammasome plays an important role, as it senses and responds to a variety of exogenous and endogenous pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs). The NLRP3 inflammasome is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoimmune and Inflammatory Disorders Research
Share to IL-33, ST2, and ILC Pathways
Share to Inflammasome and immune disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33525345
DOI: 10.3390/ijms22031271

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The NLRP3 Inflammasome and Its Role in the Pathogenicity of LeukemiaPMID 33525345Read ↗

Inflammasomes—New Contributors to Blood DiseasesSemantic proximity Read ↗

NLRP3 Inflammasome Activation in Cancer: A Double-Edged SwordSemantic proximity Read ↗

Differential role of the NLRP 3 inflammasome in infection and tumorigenesisSemantic proximity Read ↗

Targeting NLRP3 inhibits AML progression by inducing PERK/eIF2-mediated apoptosisSemantic proximity Read ↗

Role of inflammasomes in cancer immunity: mechanisms and therapeutic potentialSemantic proximity Read ↗

NLRP3 Inflammasome and Inflammatory DiseasesSemantic proximity Read ↗

Mechanisms and effects of NLRP3 in digestive cancersSemantic proximity Read ↗

Dynamic roles of inflammasomes in inflammatory tumor microenvironmentSemantic proximity Read ↗

Cell type-specific roles of NLRP3, inflammasome-dependent and -independent, in host defense, sterile necroinflammation, tissue repair, and fibrosisSemantic proximity Read ↗

Beneficial and Detrimental Roles of NLRs in CarcinogenesisSemantic proximity Read ↗

The DNA Inflammasome in Human Myeloid Cells Is Initiated by a STING-Cell Death Program Upstream of NLRP3Semantic proximity Read ↗

Targeting the NLRP3 inflammasome in chronic inflammatory diseases: current perspectivesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.