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Targeting the HERV-K102 Envelope Elicits Pyroptosis and Represents a Novel Therapeutic Strategy for Acute Myeloid Leukemia

2025-11-24

Abstract excerpt

<title>Abstract</title> <p>Objective Human endogenous retroviruses (HERVs) have been the focus of numerous recent studies. HERVs entered the human genome millions of years ago and are associated with various diseases, including cancer and immune regulation. Among them, the HERV-K family exhibits the highest transcriptional activity. However, little is known about the expression of HERVs in acute myeloid leukemia...

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Literature Corpus work
8b6f6a59-9b52-5be4-979b-114f8373107e
DOI
10.21203/rs.3.rs-7976215/v1
Open publication

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