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Liver-specific Mettl14 deletion induces nuclear heterotypia and dysregulates RNA export machinery

2024-06-17

Abstract excerpt

Modification of RNA with N 6 -methyladenosine (m 6 A) has gained attention in recent years as a general mechanism of gene regulation. In the liver, m 6 A, along with its associated machinery, has been studied as a potential biomarker of disease and cancer, with impacts on metabolism, cell cycle regulation, and pro-cancer state signaling. However these observational data have yet to be causally examined in vivo...

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Literature Corpus work
8f9058ed-034a-516d-903c-a13edc665b64
DOI
10.1101/2024.06.17.599413
Open publication

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Liver-specific Mettl14 deletion induces nuclear heterotypia and dysregulates RNA export machineryDOI 10.1101/2024.06.17.599413
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