Article
Expanded transcriptomic analysis of human hepatic stellate cells links novel coding and noncoding products to human liver fibrosis
2022-02-02
Abstract excerpt
End stage liver disease and liver failure occur primarily as a consequence of progressive fibrosis resulting from chronic liver injury. Hepatic stellate cells (HSCs) are the primary cell type responsible for production of the extracellular matrix (ECM) that forms the fibrotic scar. While the essential role of HSCs is understood, there remain no treatments that target HSCs to inhibit the development or progression...
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Identifiers and source
- Literature Corpus work
- 66f6d326-b58f-5894-b234-451f6e9ca216
- DOI
- 10.1101/2022.02.01.478715