Article

A polygenic score-based approach to identify gene-drug interactions stratifying breast cancer risk

2021-05-04

Abstract excerpt

An individual’s genetics can dramatically influence breast cancer (BC) risk. While clinical measures for prevention do exist, non-invasive personalized measures for reducing BC risk are limited. Commonly-used medications are a promising set of modifiable factors, however no previous study has explored whether a range of widely-taken approved drugs modulate BC genetics. In this study, we describe a quantitative fra...

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Literature Corpus work: 60083c6b-87fc-5aa6-9dd4-fa0c6addcfee
DOI: 10.1101/2021.05.03.21256511

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