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Article

Shared genetics between breast cancer and predisposing diseases identifies novel breast cancer treatment candidates.

Human genomics - 14 Nov 2024

Lalagkas Panagiotis N, Melamed Rachel D

Abstract excerpt

BACKGROUND: Current effective breast cancer treatment options have severe side effects, highlighting a need for new therapies. Drug repurposing can accelerate improvements to care, as FDA-approved drugs have known safety and pharmacological profiles. Some drugs for other conditions, such as metformin, an antidiabetic, have been tested in clinical trials for repurposing for breast cancer. Here, we exploit the...

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Identifiers

PMID: 39538313
DOI: 10.1186/s40246-024-00688-4
PMCID: PMC11562851

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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