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Article

Breast cancer risk during oral contraceptive use in women with high polygenic risk.

Breast cancer research : BCR - 1 Dec 2025

Chatsatourian Christina, Lo Faro Valeria, Karlsson Torgny, Hadizadeh Fatemeh, Johansson Åsa

Abstract excerpt

BACKGROUND: Oral contraceptive (OC) use is widespread globally. Despite their significant benefits, concerns persist about a potential rise in breast cancer risk linked to their use. Genetic predisposition also influences breast cancer risk; however, its interaction with OC use remains inconclusive. This study aims to explore the association between OC use and breast cancer risk in women with varying genetic...

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Identifiers

PMID: 41327462
DOI: 10.1186/s13058-025-02177-5
PMCID: PMC12690897

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