Article

Omega-3 polyunsaturated fatty acids modify glucose metabolism in THP-1 monocytes

2024-03-02

Abstract excerpt

Chronic inflammation is a driving factor in diseases like obesity and type 2 diabetes. Enhanced glucose metabolism, including via oxidative phosphorylation, may contribute to heightened immune activation. A recent clinical trial showed that supplementation with the n-3 fatty acid α-linolenic acid (ALA) reduced oxidative phosphorylation rates in human monocytes. However, the mechanism remains unknown. Therefore, o...

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Literature Corpus work: 5ffa7e05-bb5a-5f9b-bb2c-a214a1617936
DOI: 10.1101/2024.03.01.582966

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