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Article

Differential control of Yersinia pestis biofilm formation in vitro and in the flea vector by two c-di-GMP diguanylate cyclases.

PloS one - 29 Apr 2011

Sun Yi-Cheng, Koumoutsi Alexandra, Jarrett Clayton, Lawrence Kevin, Gherardini Frank C, Darby Creg, Hinnebusch B Joseph

Abstract excerpt

Yersinia pestis forms a biofilm in the foregut of its flea vector that promotes transmission by flea bite. As in many bacteria, biofilm formation in Y. pestis is controlled by intracellular levels of the bacterial second messenger c-di-GMP. Two Y. pestis diguanylate cyclase (DGC) enzymes, encoded...

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Identifiers

PMID: 21559445
DOI: 10.1371/journal.pone.0019267
PMCID: PMC3084805

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21559445-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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