Article

Quantitative input-output dynamics of a c-di-GMP signal-transduction cascade in <i>Vibrio cholerae</i>

2021-09-21

Abstract excerpt

Bacterial biofilms are multicellular communities that collectively overcome environmental threats and clinical treatments. To regulate the biofilm lifecycle, bacteria commonly transduce sensory information via the second-messenger molecule cyclic diguanylate (c-di-GMP). Using experimental and modeling approaches, we quantitatively capture c-di-GMP signal transmission via the bifunctional polyamine receptor NspS-Mb...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 976e6c80-86c8-5f79-b3bc-840b722ad4a9
DOI: 10.1101/2021.09.21.461265

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Quantitative input-output dynamics of a c-di-GMP signal-transduction cascade in <i>Vibrio cholerae</i>DOI 10.1101/2021.09.21.461265Read

Synergy between c-di-GMP and quorum-sensing signaling in <i>Vibrio cholerae</i> biofilm morphogenesisSemantic proximity Read

Shigella's c-di-GMP specific PDEs Modulate Biofilm and Virulence PhenotypesSemantic proximity Read

Cyclic diguanylate riboswitches control bacterial pathogenesis mechanismsSemantic proximity Read

A Novel Biosensor Reveals Dynamic Changes of C-di-GMP in Differentiating Cells with Ultra-High Temporal ResolutionSemantic proximity Read

c-di-GMP Turn-Over in Clostridium difficile Is Controlled by a Plethora of Diguanylate Cyclases and PhosphodiesterasesSemantic proximity Read

Shigella flexneri Diguanylate Cyclases Regulate Virulence.Semantic proximity Read

Bow-tie signaling in c-di-GMP: Machine learning in a simple biochemical network.Semantic proximity Read

High levels of cyclic diguanylate interfere with beneficial bacterial colonizationSemantic proximity Read

Prevailing concepts of c-di-GMP signaling.Semantic proximity Read

The Pseudomonas aeruginosa diguanylate cyclase GcbA, a homolog of P. fluorescens GcbA, promotes initial attachment to surfaces, but not biofilm formation, via regulation of motility.Semantic proximity Read

Cyclic Diguanylate Regulates Virulence Factor Genes via Multiple Riboswitches in Clostridium difficileSemantic proximity Read

Homologous c-di-GMP-Binding Scr Transcription Factors Orchestrate Biofilm Development in Vibrio parahaemolyticus.Semantic proximity Read