Article

Form Follows Function: A New Paradigm of Pancreatic Cancer Progression

2025-08-13

Abstract excerpt

Pancreatic ductal adenocarcinoma (PDAC) exhibits a distinctive propensity to invade nearby organs and infiltrate large blood vessels, even in the absence of distant metastasis. While the genetic and transcriptomic drivers of PDAC progression have been well studied, the mechanisms by which these molecular changes translate into functional, invasive behavior remain largely unknown. Here, we uncover a striking level...

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Literature Corpus work: 5f9395ba-0eb7-5604-9426-87d1910f998d
DOI: 10.1101/2025.08.12.667175

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