Article

Integrated spatial morpho-transcriptomics predicts functional traits in pancreatic cancer

2025-03-14

Abstract excerpt

Analyses of patient-derived cell lines have greatly enhanced discovery of molecular biomarkers and therapeutic targets. However, characterization of cellular morphological properties is limited. We studied cell morphologies of human pancreatic adenocarcinoma (PDAC) cell lines and their associations with drug sensitivity, gene expression, and functional properties. By integrating live cell and spatial mRNA imaging,...

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Literature Corpus work: d37e6f1f-d504-557b-b9b1-258831fe4fb9
DOI: 10.1101/2025.03.12.642933

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