Article
Regulation of neuronal input transformations by tunable dendritic inhibition.
Nature neuroscience - 15 Jan 2012
Lovett-Barron Matthew, Turi Gergely F, Kaifosh Patrick, Lee Peter H, Bolze Frédéric, Sun Xiao-Hua, Nicoud Jean-François, Zemelman Boris V, Sternson Scott M, Losonczy Attila
Abstract excerpt
Transforming synaptic input into action potential output is a fundamental function of neurons. The pattern of action potential output from principal cells of the mammalian hippocampus encodes spatial and nonspatial information, but the cellular and circuit mechanisms by which neurons transform their synaptic input into a given output are unknown. Using a combination of optical activation and cell type-specific...
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