Article

Interactions of SARS-CoV-2 envelope protein with amilorides correlate with antiviral activity

2021-04-06

Abstract excerpt

SARS-CoV-2 is the novel coronavirus that is the causative agent of COVID-19, a sometimes-lethal respiratory infection responsible for a world-wide pandemic. The envelope (E) protein, one of four structural proteins encoded in the viral genome, is a 75-residue integral membrane protein whose transmembrane domain exhibits ion channel activity and whose cytoplasmic domain participates in protein-protein interactions....

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Literature Corpus work: 5f867ab8-939d-5b4a-8555-10f44c7cfa12
DOI: 10.1101/2021.04.06.438579

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