Article

Role of α-tubulin helix 11’ in heterodimer conformation and microtubule dynamics

2026-02-17

Abstract excerpt

Tubulin heterodimers transition from a curved conformation in solution to straight conformation when assembled into the microtubule lattice. Many proteins and small molecules alter microtubule dynamics by binding and stabilizing the curved or straight conformations; however, we have a poor understanding of the regions of the tubulin heterodimer that contribute to this transition and whether these conformations rep...

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Identifiers and source

Literature Corpus work: 5f4057c3-5a80-5d99-9345-63505c25d228
DOI: 10.64898/2026.02.16.705813

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