Article

c-Jun regulates postpartum β-cell apoptosis and survival downstream of prolactin signaling

2025-02-27

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objective</h4> Pregnancy and postpartum states drive dynamic expansion and regression of maternal β-cell mass. Little is known about what regulates postpartum regression. We recently profiled murine islets at different time points from late gestation to early postpartum to identify regulators of β-cell apoptosis or survival. One hit was c-Jun, a transcription factor which regulates prolifer...

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Literature Corpus work: 5f1f7e8f-0c30-5a6e-8485-d5d1d8edc793
DOI: 10.1101/2025.02.26.640362

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