Article

SOX15 regulates stem cell pluripotency and promotes neural fate during differentiation by activating <i>Hes5</i>

2022-04-25

Abstract excerpt

SOX2 and SOX15 are Sox family transcription factors enriched in embryonic stem cells (ESCs). The role of SOX2 in activating gene expression programs essential for stem cell self-renewal and acquisition of pluripotency during somatic cell reprogramming is well-documented. However, the contribution of SOX15 to these processes is unclear and often presumed redundant with SOX2 because both transcription factors displa...

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Literature Corpus work: 5eb39bc6-b5fe-5572-b243-d4ec5bd4ca5f
DOI: 10.1101/2022.04.25.489402

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