Article
Differential roles for Sox15 and Sox2 in transcriptional control in mouse embryonic stem cells.
The Journal of biological chemistry - 1 Jul 2005
Maruyama Masayoshi, Ichisaka Tomoko, Nakagawa Masato, Yamanaka Shinya
Abstract excerpt
Sox family transcription factors play essential roles in cell differentiation, development, and sex determination. Sox2 was previously thought to be the sole Sox protein expressed in mouse embryonic stem (ES) cells. Sox2 associates with Oct3/4 to maintain self-renewal of ES cells. In the current study, digital differential display identified transcripts for an additional Sox family member, Sox15, enriched in...
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