Back to search

Article

Benchmarking fragmentation-derived artificial cfDNA reference standards

2026-08-17

Abstract excerpt

An important step toward clinical implementation of (epi-)genomic assays on liquid biopsies is their validation on identical samples within and across laboratories. For these validation studies, there is a need for cell-free DNA (cfDNA) samples with defined tumor fractions and (epi-)genomic aberrations. However, the amount of circulating cfDNA isolated from patient samples is often limited, especially in pediatric...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
5eb34450-6060-5fed-ae1e-18f4ec627370
DOI
10.64898/2026.08.12.744389
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Benchmarking fragmentation-derived artificial cfDNA reference standardsDOI 10.64898/2026.08.12.744389
Cell-Free DNA: Features and Attributes Shaping the Next Frontier in Liquid BiopsySemantic proximity
Cell-Free DNA Fragmentomics in Liquid BiopsySemantic proximity
FinaleDB: a browser and database of cell-free DNA fragmentation patternsSemantic proximity
DNA methylation analysis explores the molecular basis of plasma cell-free DNA fragmentationSemantic proximity
Collection of cell-free DNA for genomic analysis of solid tumors in a clinical laboratory settingSemantic proximity
Cell‐free DNA‐associated multi‐feature applications in cancer diagnosis and treatmentSemantic proximity
Cancer-like fragmentomic characteristics of somatic variants in cell-free DNASemantic proximity
Quantitative characterization of tumor cell-free DNA shortening.Semantic proximity
Cell-Free DNA Fragmentomics: The Novel Promising BiomarkerSemantic proximity
Modelling clinical DNA fragmentation in the development of universal PCR-based assays for bisulfite, FFPE and cfDNA sample analysisSemantic proximity
Genome-wide cell-free DNA fragmentation in patients with cancerSemantic proximity
Cell-free DNA end characteristics enable accurate and sensitive cancer diagnosisSemantic proximity
Select a neighboring publication to make it the new centre.