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Collection of cell-free DNA for genomic analysis of solid tumors in a clinical laboratory setting

27 Apr 2017

Abstract excerpt

The breadth of diagnostic procedures that utilize cell free DNA (cfDNA) from human plasma has increased dramatically in recent years. Here, we confirm that tumor-derived cfDNA fragments are similar in size distribution to cfDNA derived from normal tissues. Therefore, collection procedures optimized with healthy donor specimens are likely to be applicable to the diagnosis and monitoring of many different cancer...

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PMID: 28448587
DOI: 10.1371/journal.pone.0176241

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