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Integrated Transcriptomic and Mendelian Randomization Analyses Identify Novel Biomarkers of Depression and Diabetes Comorbidity

2026-06-12

Abstract excerpt

<title>Abstract</title> <p> Objective: Type 2 diabetes mellitus (DM) and depressive disorder (DD) frequently co-occur; however, the mechanisms underlying their comorbidity remain insufficiently understood. Therefore, the aim of this study was to explore the immune dysregulation mechanisms involved in the pathogenesis of DM and DD. Transcriptomic profiling was integrated with Mendelian randomization (MR) to inves...

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Literature Corpus work
5eaa45a1-3fea-5519-87d4-6c07b5a4829d
DOI
10.21203/rs.3.rs-9633629/v1
Open publication

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Integrated Transcriptomic and Mendelian Randomization Analyses Identify Novel Biomarkers of Depression and Diabetes ComorbidityDOI 10.21203/rs.3.rs-9633629/v1
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