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Article

Analysis of the Genetic Comorbid Mechanisms of Type 2 Diabetes, Alzheimer's Disease, and Hypertension Using Network Modularization.

BioMed research international - 1 Jan 2026

Tian Siwei, Zong Wenjing, Zeng Ziling, Wang Jingai, Niu Qikai, Zhang Siqi, Zhang Huamin, Li Bing

Abstract excerpt

Background: Type 2 diabetes mellitus (T2DM), Alzheimer's disease (AD), and hypertension (HTN) tend to be comorbidities and mutually influence each other; however, the mechanisms underlying their association remain unclear. This study was aimed at identifying genes associated with susceptibility to these three diseases and their mechanisms of action using integrated network modularization analysis. Methods: The...

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Topics

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Share to Alzheimer Disease
Share to Comorbidity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Databases, Genetic

Share to Diabetes Mellitus, Type 2

Share to Gene Expression Profiling

Share to Gene Regulatory Networks

Share to Hypertension

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Source

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Identifiers

PMID: 41717317
DOI: 10.1155/bmri/8877510
PMCID: PMC12914336

Genes

ACTN4
BGN
ELAVL1
NRF1
SUMO2
TSFM
UBC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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