Article

Role of MicroRNA in Hydroxyurea mediated HbF induction in Sickle cell anaemia patients

2022-06-17

Abstract excerpt

<h4>Background: </h4> Hydroxyurea (HU) is found to be beneficial in Sickle cell Anaemia (SCA) patients, due to its ability to increase foetal haemoglobin (HbF), however, patients show a variable response. Differences in HbF levels are attributed to many factors; but, the role of miRNA in HbF regulation is sparsely investigated. <h4>Materials: </h4> and Methods: In this study, we evaluated the effect of miRNA expre...

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Literature Corpus work: 5e56a5ea-ffe9-53d1-b978-3cea5f5318bd
DOI: 10.21203/rs.3.rs-1712589/v1

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