Article

Maternal age and genome-wide failure of meiotic recombination are associated with triploid conceptions in humans

2025-02-17

Abstract excerpt

Triploid and haploid conceptions are not viable and are a common occurrence in humans, where they account for 10% of all pregnancy losses. Despite the parent-of-origin being important in the etiology of the pregnancy, our knowledge of their causes is limited, especially at the point of conception. Using a dataset of 96,660 biopsies and a validation dataset of 44,324 from human blastocysts embryos generated by intr...

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Literature Corpus work: 5e5650dd-f568-50ea-996d-386c92af804f
DOI: 10.1101/2025.02.15.637872

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