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The cytogenetics of polar bodies: insights into female meiosis and the diagnosis of aneuploidy

14 Apr 2011

Abstract excerpt

Female meiosis is comprised by two cell divisions, meiosis I (MI) and II (MII) and two different stages at which the development of the oocyte is temporarily halted. In the case of MI, this pause can potentially last for four to five decades. This added layer of complexity distinguishes female gametogenesis from its male counterpart. The single most important genetic factor impacting human reproductive success is...

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PMID: 21493685
DOI: 10.1093/molehr/gar024

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