Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Recurrent triploidy due to a failure to complete maternal meiosis II: whole-exome sequencing reveals candidate variants.

Molecular human reproduction - 1 Apr 2015

Filges I, Manokhina I, Peñaherrera M S, McFadden D E, Louie K, Nosova E, Friedman J M, Robinson W P

Abstract excerpt

Triploidy is a relatively common cause of miscarriage; however, recurrent triploidy has rarely been reported. A healthy 34-year-old woman was ascertained because of 18 consecutive miscarriages with triploidy found in all 5 karyotyped losses. Molecular results in a sixth loss were also consistent with triploidy. Genotyping of markers near the centromere on multiple chromosomes suggested that all six triploid...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Abnormal Karyotype
Share to Abortion, Habitual

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to High-Throughput Nucleotide Sequencing

Share to Meiosis

Share to Pregnancy

Share to Receptors, Steroid

Share to Triploidy

Source

Open in PubMed Open full text

Identifiers

PMID: 25504873
DOI: 10.1093/molehr/gau112
PMCID: PMC4381034

Genes

OSBPL5
PLCD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Recurrent triploidy due to a failure to complete maternal meiosis II: whole-exome sequencing reveals candidate variants.PMID 25504873Read ↗

Maternal age and genome-wide failure of meiotic recombination are associated with triploid conceptions in humansSemantic proximity Read ↗

Whole exome sequencing in unexplained recurrent miscarriage families identified novel pathogenic genetic causes of euploid miscarriage.Semantic proximity Read ↗

Biallelic variant in cyclin B3 is associated with failure of maternal meiosis II and recurrent digynic triploidySemantic proximity Read ↗

Genetic Variants in Recurrent Euploid Pregnancy LossSemantic proximity Read ↗

Maternal genetic variants associated with aneuploid conception: a narrative review.Semantic proximity Read ↗

Prioritization of putatively detrimental variants in euploid miscarriages.Semantic proximity Read ↗

Novel variants in MEI1 cause female infertility characterized by early embryonic arrest and implantation failure.Semantic proximity Read ↗

Identification of chromosomal abnormalities in miscarriages using single-nucleotide polymorphism arrays.Semantic proximity Read ↗

Tripolar mitosis drives the association between maternal genotypes of <i>PLK4</i> and aneuploidy in human preimplantation embryosSemantic proximity Read ↗

Copy Number Variants in Premature Ovarian Failure and Ovarian DysgenesisSemantic proximity Read ↗

Tripolar chromosome segregation drives the association between maternal genotype at variants spanning PLK4 and aneuploidy in human preimplantation embryos.Semantic proximity Read ↗

Cytogenetic analysis of miscarriages from couples with recurrent miscarriage: a case-control studySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.