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LNCaP Atlas: Gene expression associated with in vivoprogression to castration-recurrent prostate cancer

24 Sept 2010

Abstract excerpt

BACKGROUND: There is no cure for castration-recurrent prostate cancer (CRPC) and the mechanisms underlying this stage of the disease are unknown. METHODS: We analyzed the transcriptome of human LNCaP prostate cancer cells as they progress to CRPC in vivo using replicate LongSAGE libraries. We refer to these libraries as the LNCaP atlas and compared these gene expression profiles with current suggested models of...

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PMID: 20868494
DOI: 10.1186/1755-8794-3-43

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