Article

Synergic microRNAs suppress human glioblastoma progression by modulating clinically relevant targets

2025-04-01

Abstract excerpt

<h4>ABSTRACT</h4> Glioblastoma (GBM) is a highly aggressive brain tumor characterized by therapy-resistant glioma stem-like cells (GSCs) and extensive infiltration into surrounding brain tissue. MicroRNAs (miRNAs) are post-transcriptional regulators of oncogenic pathways, but their tumor-suppressive function is frequently lost in GBM. This study explores a multimodal therapeutic approach by restoring a combinatio...

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Literature Corpus work: 5dfde938-9298-5171-993a-d4a5e7631628
DOI: 10.1101/2025.03.27.645741

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