Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Up-regulation of miR-663a inhibits the cancer stem cell-like properties of glioma via repressing the KDM2A-mediated TGF-β/SMAD signaling pathway

23 Aug 2021

Abstract excerpt

Emerging reports have shown that microRNAs (miRNAs) function as vital regulators in tumor development via modulating gene expression at the posttranscriptional level. Here, we explored the role and underlying mechanism of miR-663a in the proliferation, migration, invasion, and cancer stem cell-like (CSC) properties of glioma cells. Quantitative reverse transcription PCR (qRT‐PCR) was implemented to detect...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cancer-related molecular mechanisms research
Share to MicroRNA in disease regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34424812
DOI: 10.1080/15384101.2021.1966962

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Up-regulation of miR-663a inhibits the cancer stem cell-like properties of glioma via repressing the KDM2A-mediated TGF-β/SMAD signaling pathwayPMID 34424812Read ↗

Gremlin1 promotes carcinogenesis of glioma in vitroSemantic proximity Read ↗

RUNX2 mediated epithelial mesenchymal transition induced by TGF beta and Smad signaling promotes malignant progression in gliomaSemantic proximity Read ↗

LncRNA NEAT1 promotes malignant phenotypes and TMZ resistance in glioblastoma stem cells by regulating let-7g-5p/MAP3K1 axisSemantic proximity Read ↗

RRM2 promotes the progression of human glioblastomaSemantic proximity Read ↗

Synergic microRNAs suppress human glioblastoma progression by modulating clinically relevant targetsSemantic proximity Read ↗

miR-135b suppresses tumorigenesis in glioblastoma stem-like cells impairing proliferation, migration and self-renewal.Semantic proximity Read ↗

Long Non-Coding RNA LINC00663 Promotes Gliomagenesis and ProgressionSemantic proximity Read ↗

Super-Enhancer-Associated TMEM44-AS1 Aggravated Glioma Progression by Forming a Positive Feedback Loop With MycSemantic proximity Read ↗

MELK inhibition effectively suppresses growth of glioblastoma and cancer stem-like cells by blocking AKT and FOXM1 pathwaysSemantic proximity Read ↗

miRNA Multiplayers in glioma. From bench to bedside.Semantic proximity Read ↗

LncRNA TMPO-AS1 Promotes Proliferation and Invasion by Sponging miR-383-5p in Glioma CellsSemantic proximity Read ↗

GAS5 Attenuates Malignant Progression of Glioma Stem-like Cells via Regulating E-cadherinSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.