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Knockdown of PYCR1 inhibits proliferation, migration, and invasion in oesophageal squamous cell cancer by limiting its interaction with EGFR

2022-06-01

Abstract excerpt

<h4>Background: </h4> The expression and functions of pyrroline‐5‐carboxylate reductase 1 (PYCR1) in oesophageal squamous cell cancer (ESCC) are obscure. Here, we aimed to investigate the role of PYCR1 in ESCC. <h4>Methods: </h4>: Immunohistochemistry with a human oesophageal cancer tissue microarray was used to assessPYCR1 levels in ESCC tissues and RT-qPCR was used to measure PYCR1 in ESCC cell lines. PYCR1 was...

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Identifiers and source

Literature Corpus work
5df13255-c472-5995-af6c-a8af3654fb3e
DOI
10.21203/rs.3.rs-1706403/v1
Open publication

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Knockdown of PYCR1 inhibits proliferation, migration, and invasion in oesophageal squamous cell cancer by limiting its interaction with EGFRDOI 10.21203/rs.3.rs-1706403/v1
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