Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

FGFR1 signaling potentiates tumor growth and predicts poor prognosis in esophageal squamous cell carcinoma patients

19 Dec 2017

Abstract excerpt

Fibroblast growth factor receptor-1 (FGFR1) over-expression was broadly found in squamous cancer, where it induced cellular proliferation, differentiation, and metastasis by activating various signaling pathway. However, the role of FGFR1 gene expression in predicting prognosis of Esophageal Squamous Cell Carcinoma (ESCC) and its regulatory function in the progression of ESCC are not well understood. Therefore,...

Topics

Join the communities discussing this publication.

Esophageal Cancer Research and Treatment
Fibroblast Growth Factor Research
Kruppel-like factors research

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 29257923
DOI: 10.1080/15384047.2017.1394541

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

FGFR1 signaling potentiates tumor growth and predicts poor prognosis in esophageal squamous cell carcinoma patientsPMID 29257923Read ↗

Prognostic implications of FGFR1 and MYC status in esophageal squamous cell carcinoma.Semantic proximity Read ↗

FAT1 prevents epithelial mesenchymal transition (EMT) via MAPK/ERK signaling pathway in esophageal squamous cell cancer.Semantic proximity Read ↗

E2F transcription factor 1 is involved in the phenotypic modulation of esophageal squamous cell carcinoma cells via microRNA-375.Semantic proximity Read ↗

FOXK1 regulates malignant progression and radiosensitivity through direct transcriptional activation of CDC25A and CDK4 in esophageal squamous cell carcinomaSemantic proximity Read ↗

Effects of EFNA1 on cell phenotype and prognosis of esophageal carcinoma.Semantic proximity Read ↗

FGF1-FGFR1 axis promotes tongue squamous cell carcinoma (TSCC) metastasis through epithelial-mesenchymal transition (EMT).Semantic proximity Read ↗

FGFR2 maintains cancer cell differentiation via AKT signaling in esophageal squamous cell carcinomaSemantic proximity Read ↗

A novel long non-coding RNA GK-IT1 promotes the carcinogenesis and progression of esophageal squamous cell carcinoma via mediating the phosphorylation of MAPK1Semantic proximity Read ↗

V-Raf murine sarcoma viral oncogene homolog B1 (BRAF) as a prognostic biomarker of poor outcomes in esophageal cancer patients.Semantic proximity Read ↗

Role of FGF Receptors as an Emerging Therapeutic Target in Lung Squamous Cell CarcinomaSemantic proximity Read ↗

LncRNA NCK1-AS1 Was Overexpressed in Esophageal Squamous Cell Carcinoma and Predicts SurvivalSemantic proximity Read ↗

LncRNA NCK1-AS1 is overexpressed in esophageal squamous cell carcinoma and predicts survivalSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.