Article

Functional Role of FUNDC1 in ESCC Progression via Modulation of Mitochondrial Fission and HMGB1/PI3K/Akt Signalling

2026-04-02

Abstract excerpt

<title>Abstract</title> <p> This study investigates the functional role of FUNDC1 in the progression of esophageal squamous cell carcinoma (ESCC). Transcriptomic analysis using the Cancer Genome Atlas (TCGA) dataset revealed that FUNDC1 is significantly overexpressed in ESCC tissues and is associated with unfavourable patient prognosis. <italic>In vitro</italic> assays demonstrated that silencing FUNDC1 suppre...

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Literature Corpus work: d94e4f33-80b1-5c37-9d64-c71a03c85844
DOI: 10.21203/rs.3.rs-9004020/v1

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