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Deciphering the effects of PYCR family on cell function, prognostic value, immune infiltration in ccRCC and pan-cancer

2024-04-17

Abstract excerpt

<h4>Background: </h4> Pyrroline-5-carboxylate reductase (PYCR) is pivotal in converting pyrroline-5-carboxylate (P5C) to proline, the final step in proline synthesis. Three isoforms, PYCR1, PYCR2, and PYCR3, existed and played significant regulatory roles in tumor initiation and progression. Methods In this study, we firstly assessed molecular and immune characteristics of PYCRs by a pan-cancer analysis, especial...

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Literature Corpus work
58c25dcf-5e3e-5e3f-bcea-d53e70f2b61b
DOI
10.21203/rs.3.rs-4231917/v1
Open publication

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Deciphering the effects of PYCR family on cell function, prognostic value, immune infiltration in ccRCC and pan-cancerDOI 10.21203/rs.3.rs-4231917/v1
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