Article

The γ-secretase catalytic subunit PSEN1, regulated by YY1, promotes lung adenocarcinoma progression via the Notch1/EGFR pathway

2024-09-04

Abstract excerpt

<title>Abstract</title> <p><bold>Backgroud:</bold> Serving as a pivotal catalytic component of the γ-secretase, PSEN1 is recognized for its significant influence on the initiation and advancement of tumors. Nevertheless, the specific function and the fundamental mechanisms by which PSEN1 contributes to lung adenocarcinoma (LUAD) are yet to be elucidated. This study aimed to elucidate the role and regulation mecha...

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Literature Corpus work: fa41e2a6-f322-5655-83a3-179c4593eb21
DOI: 10.21203/rs.3.rs-4811218/v1

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