Article

<em>BTN2A1</em> and <em>BTN3A1</em> as Novel Coeliac Disease Risk Loci: An <em>in silico</em> Analysis

2025-09-22

Abstract excerpt

Coeliac disease (CeD) is a gastrointestinal enteropathy triggered by the consumption of gluten in predisposed individuals. Only around 50% of CeD genetic risk is understood, with the majority of risk attributed to the HLA loci. We investigated the butyrophilin family of immunomodulators as novel CeD risk loci. We sequenced the butyrophilin loci of 48 CeD and 46 control patients and carried out gene-based burden te...

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Literature Corpus work: 5db86a56-e3c8-536b-8b34-fff4a5ec3191
DOI: 10.20944/preprints202509.1772.v1

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