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Article

Phenome-wide Mendelian randomization analysis reveals multiple health comorbidities of coeliac disease.

EBioMedicine - 1 Mar 2024

Yuan Shuai, Jiang Fangyuan, Chen Jie, Lebwohl Benjamin, Green Peter H R, Leffler Daniel, Larsson Susanna C, Li Xue, Ludvigsson Jonas F

Abstract excerpt

BACKGROUND: Coeliac disease (CeD) has been associated with a broad range of diseases in observational data; however, whether these associations are causal remains undetermined. We conducted a phenome-wide Mendelian randomization analysis (MR-PheWAS) to investigate the comorbidities of CeD. METHODS: Single nucleotide polymorphisms (SNPs) associated with CeD at the genome-wide significance threshold and without...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38382313
DOI: 10.1016/j.ebiom.2024.105033
PMCID: PMC10900254

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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