Article

The Nonequilibrium Mechanism of Noise Enhancer synergizing with Activator in HIV Latency Reactivation

2020-01-15

Abstract excerpt

<h4>Summary</h4> Reactivating HIV latency and then simultaneously eliminating it by antiretroviral therapy has become a leading strategy in curing HIV. Recently, single-cell screening experiments have shown the drug synergy between two categories of biomolecules, Activators (AC) and Noise Enhancers (NE): NE can amplify the reactivation of latent HIV induced by AC, although NE itself cannot reactivate HIV latency....

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Literature Corpus work: 5db7de39-4bd4-5916-a666-a392591615dd
DOI: 10.1101/2020.01.14.905653

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