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New latency-promoting agents for a block-and-lock functional cure strategy

27 Feb 2024

Abstract excerpt

PURPOSE OF REVIEW: Currently, HIV-infected patients are treated with antiretroviral therapy. However, when the treatment is interrupted, viral rebound occurs from latently infected cells. Therefore, scientists aim to develop an HIV-1 cure which eradicates or permanently silences the latent reservoir. RECENT FINDINGS: Previously, scientists focused on the shock-and-kill cure strategy, which aims to eradicate the...

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PMID: 38457209
DOI: 10.1097/coh.0000000000000844

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