Article

Targeting HIV at its core: A mathematical model for optimizing Tat Inhibitor-based therapies toward enhanced functional cure strategies

2026-04-15

Abstract excerpt

Human immunodeficiency virus (HIV) persistence remains a major barrier to cure due to the existence of long-lived latent reservoirs that evade immune clearance and persist despite combination antiretroviral therapy (ART). Although ART effectively suppresses viral replication, treatment interruption often leads to rapid viral rebound originating from these latent reservoirs. In this study, we develop a deterministi...

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Literature Corpus work: b44e4fca-3060-5ac8-94c2-6cb53c77d146
DOI: 10.64898/2026.04.13.718184

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