Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Forging a Functional Cure for HIV: Transcription Regulators and Inhibitors

7 Sept 2022

Abstract excerpt

Current antiretroviral therapy (ART) increases the survival of HIV-infected individuals, yet it is not curative. The major barrier to finding a definitive cure for HIV is our inability to identify and eliminate long-lived cells containing the dormant provirus, termed viral reservoir. When ART is interrupted, the viral reservoir ensures heterogenous and stochastic HIV viral gene expression, which can reseed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to HIV/AIDS drug development and treatment
Share to HIV/AIDS Research and Interventions
Share to HIV Research and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36146786
DOI: 10.3390/v14091980

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Forging a Functional Cure for HIV: Transcription Regulators and InhibitorsPMID 36146786Read ↗

Breaking the Silence: Regulation of HIV Transcription and Latency on the Road to a CureSemantic proximity Read ↗

Key Players in HIV-1 Transcriptional Regulation: Targets for a Functional CureSemantic proximity Read ↗

Curing HIV: Pharmacologic Approaches to Target HIV-1 LatencySemantic proximity Read ↗

A broad drug arsenal to attack a strenuous latent HIV reservoirSemantic proximity Read ↗

The Block-and-Lock Strategy for Human Immunodeficiency Virus Cure: Lessons Learned from Didehydro–Cortistatin ASemantic proximity Read ↗

HIV-1 Latency and Viral Reservoirs: Existing Reversal Approaches and Potential Technologies, Targets, and Pathways Involved in HIV Latency StudiesSemantic proximity Read ↗

Block-And-Lock: New Horizons for a Cure for HIV-1Semantic proximity Read ↗

Silencing the transcriptionally active HIV reservoir to improve treatment outcomesSemantic proximity Read ↗

The Current Status of Latency Reversing Agents for HIV-1 RemissionSemantic proximity Read ↗

A New Small-Molecule Compound, Q308, Silences Latent HIV-1 Provirus by Suppressing Tat- and FACT-Mediated TranscriptionSemantic proximity Read ↗

Lost in Transcription: Molecular Mechanisms that Control HIV LatencySemantic proximity Read ↗

Depicting HIV-1 Transcriptional Mechanisms: A Summary of What We KnowSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.