Article

The kinesin motor KIF1C is a putative transporter of the exon junction complex in neuronal cells

2022-08-25

Abstract excerpt

Neurons critically depend on regulated RNA localization and tight control of spatio-temporal gene expression to maintain their morphological and functional integrity. Mutations in the kinesin motor protein gene KIF1C cause Hereditary Spastic Paraplegia, an autosomal recessive disease leading to predominant degeneration of the long axons of central motoneurons. In this study we aimed to gain insight into the molec...

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Literature Corpus work: 3463d6b0-6862-5680-bedb-97479369159f
DOI: 10.1101/2022.08.24.505074

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