Article
KIF5A and the contribution of susceptibility genotypes as a predictive biomarker for multiple sclerosis.
Journal of neurology - 1 Jun 2021
Hares Kelly, Kemp K, Loveless S, Rice C M, Scolding N, Tallantyre E, Robertson N, Wilkins A
Abstract excerpt
There is increasing interest in the development of multiple sclerosis (MS) biomarkers that reflect central nervous system tissue injury to determine prognosis. We aimed to assess the prognostic value of kinesin superfamily motor protein KIF5A in MS by measuring levels of KIF5A in cerebrospinal fluid (CSF) combined with analysis of single nucleotide polymorphisms (SNPs; rs12368653 and rs703842) located within a MS...
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