Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Overexpression of Kinesin Superfamily Motor Proteins in Alzheimer’s Disease

17 Oct 2017

Abstract excerpt

Defects in motor protein-mediated neuronal transport mechanisms have been implicated in a number of neurodegenerative disorders but remain relatively little studied in Alzheimer's disease (AD). Our aim in the present study was to assess the expression of the anterograde kinesin superfamily motor proteins KIF5A, KIF1B, and KIF21B, and to examine their relationship to levels of hyperphosphorylated tau, amyloid-β...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Cellular transport and secretion
Share to Microtubule and mitosis dynamics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29060936
DOI: 10.3233/jad-170094

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Overexpression of Kinesin Superfamily Motor Proteins in Alzheimer’s DiseasePMID 29060936Read ↗

KIF5A and KLC1 expression in Alzheimer’s disease: relationship and genetic influencesSemantic proximity Read ↗

Axonal motor protein KIF5A and associated cargo deficits in multiple sclerosis lesional and normal-appearing white matter.Semantic proximity Read ↗

Differential expression of molecular motors in the motor cortex of sporadic ALS.Semantic proximity Read ↗

One gene, many phenotypes: the role of KIF5A in neurodegenerative and neurodevelopmental diseases.Semantic proximity Read ↗

Altered molecular and cellular mechanisms in KIF5A-associated neurodegenerative or neurodevelopmental disorders.Semantic proximity Read ↗

Reduced axonal motor protein expression in non-lesional grey matter in multiple sclerosisSemantic proximity Read ↗

Abundant kif21b is associated with accelerated progression in neurodegenerative diseases.Semantic proximity Read ↗

ALS-Associated KIF5A Mutation Causes Locomotor Deficits Associated with Cytoplasmic Inclusions, Alterations of Neuromuscular Junctions, and Motor Neuron Loss.Semantic proximity Read ↗

Investigating how changes in the levels of kinesins impact neuronal health in Drosophila and human iPSC-derived neurons AD model.Semantic proximity Read ↗

Familial Alzheimer’s disease mutation undermines axonal transport by enhancing dynactin recruitment to the APP motor assembliesSemantic proximity Read ↗

KIF5A binds RNA to orchestrate synaptic mRNA localization and stress granules in ALSSemantic proximity Read ↗

An ALS-associated KIF5A mutant forms oligomers and aggregates and induces neuronal toxicitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.