Article

Neuronal network activity controls microglial process surveillance in awake mice via norepinephrine signaling

2019-02-22

Abstract excerpt

Microglia are resident immune cells that dynamically survey the brain parenchyma, interacting with neurons in both health and disease. However, it is still unclear how neuronal network activity drives microglial dynamics. Utilizing in vivo two-photon imaging of microglia in awake mice, we found that inhibition of neuronal activity under general anesthesia dramatically increased microglial process surveillance. Ac...

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Literature Corpus work: 5d7ac722-7db2-5625-9d42-3e0cebc8d3ab
DOI: 10.1101/557686

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