Article

Deficiency of the Heterogeneous Nuclear Ribonucleoprotein U locus leads to delayed hindbrain neurogenesis

2022-09-17

Abstract excerpt

<h4>ABSTRACT</h4> Genetic variants affecting Heterogeneous Nuclear Ribonucleoprotein U (HNRNPU) have been identified in several neurodevelopmental disorders (NDDs). HNRNPU is widely expressed in the human brain and shows the highest postnatal expression in the cerebellum. Recent studies have investigated the role of HNRNPU in cerebral cortical development, but the effects of HNRNPU deficiency on cerebellar dev...

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Literature Corpus work: 5d60f766-fd53-569d-80f7-fcd92674d109
DOI: 10.1101/2022.09.14.507275

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