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Article

Roles of SNORD115 and SNORD116 ncRNA clusters in neuronal differentiation

2023-10-24

Abstract excerpt

<h4>ABSTRACT</h4> Prader-Willi syndrome shows features linked to brain development and hypothalamus-related endocrine abnormalities. The smallest clinical deletions fall within the large (∼650Kb) SNHG14 gene, removing 29 consecutive introns that each generate SNORD116. SNHG14 also includes 48 tandem introns encoding SNORD115 and generates multiple, extended snoRNA-related species. SNORD115 and SNORD116 resemble b...

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Literature Corpus work
dba19c18-08e4-5560-ac74-07933d2ed7e4
DOI
10.1101/2023.10.24.563766
Open publication

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Roles of SNORD115 and SNORD116 ncRNA clusters in neuronal differentiationDOI 10.1101/2023.10.24.563766
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