Article

Angiotensin-converting enzyme (<i>ACE1, ACE2</i>) gene variants are associated with COVID19 severity depending on the hypertension status

2020-06-12

Abstract excerpt

<h4>Background</h4> The Angiotensin system is implicated in the pathogenesis of COVID19. First, ACE2 is the cellular receptor for SARS-COv-2, and expression of the ACE2 gene could regulate the individual’s susceptibility to infection. In addition, the balance between ACE1 and ACE activity has been implicated in the pathogenesis of respiratory diseases and could play a role in the severity of COVID19. Functional AC...

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Literature Corpus work: 5d3ee97c-a181-5a18-b6d1-df6cce563af6
DOI: 10.1101/2020.06.11.20128033

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