Variants in ACE2; potential influences on virus infection and COVID-19 severity.

doi:10.1016/j.meegid.2021.104773

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Article

Variants in ACE2; potential influences on virus infection and COVID-19 severity.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jun 2021

Bakhshandeh Behnaz, Sorboni Shokufeh Ghasemian, Javanmard Amir-Reza, Mottaghi Seyed Saeed, Mehrabi Mohammad-Reza, Sorouri Farzaneh, Abbasi Ardeshir, Jahanafrooz Zohreh

Abstract excerpt

The third pandemic of coronavirus infection, called COVID-19 disease, was first detected in November 2019th. Various determinants of disease progression such as age, sex, virus mutations, comorbidity, lifestyle, host immune response, and genetic background variation have caused clinical variability of COVID-19. The causative agent of COVID-19 is an enveloped coronavirus named severe acute respiratory syndrome...

Topics

Angiotensin-Converting Enzyme 2
COVID-19
Cytokine Release Syndrome
Disease Management
Disease Susceptibility
Genetic Variation
Host-Pathogen Interactions
Humans
Immune Evasion

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Immunity, Innate

Polymorphism, Single Nucleotide

Prognosis

Protein Binding

Receptors, Virus

SARS-CoV-2

Severity of Illness Index

Source

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Identifiers

PMID: 33607284
DOI: 10.1016/j.meegid.2021.104773
PMCID: PMC7886638

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