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Article

Genotype variation of ACE and ACE2 genes affects the severity of COVID-19 patients.

BMC research notes - 4 Sept 2023

Faustine Ingrid, Marteka Deli, Malik Amarila, Supriyanto Eko, Syafhan Nadia F

Abstract excerpt

OBJECTIVE: Genetic polymorphisms in ACE and ACE2 genes are involved in the RAS regulation of blood pressure and their activity may confer susceptibility to hypertension. In addition, they may play a role in SARS-CoV-2 pathogenesis and the severity of COVID-19. This study aims to determine the effect of genetic variations in the ACE (rs4331) and ACE2 (rs2074192) genes with hypertension comorbidity on the severity...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37667339
DOI: 10.1186/s13104-023-06483-z
PMCID: PMC10478384

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