Angiotensin-Converting Enzyme (ACE) 1 Gene Polymorphism and Phenotypic Expression of COVID-19 Symptoms.

doi:10.3390/genes12101572

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Article

Angiotensin-Converting Enzyme (ACE) 1 Gene Polymorphism and Phenotypic Expression of COVID-19 Symptoms.

Genes - 1 Oct 2021

Yamamoto Naoki, Nishida Nao, Yamamoto Rain, Gojobori Takashi, Shimotohno Kunitada, Mizokami Masashi, Ariumi Yasuo

Abstract excerpt

The renin-angiotensin-aldosterone system (RAAS) appears to play an important role in SARS-CoV-2 infection. Polymorphisms within the genes that control this enzymatic system are candidates for elucidating the pathogenesis of COVID-19, since COVID-19 is not only a pulmonary disease but also affects many organs and systems throughout the body in multiple ways. Most striking is the fact that ACE2, one of the major...

Topics

COVID-19
Gene Expression Regulation, Viral
Genotype
Humans
INDEL Mutation
Peptidyl-Dipeptidase A
Polymorphism, Genetic
Risk Factors
SARS-CoV-2

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Identifiers

PMID: 34680966
DOI: 10.3390/genes12101572
PMCID: PMC8535484

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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