Article
Angiotensin-Converting Enzyme (ACE) 1 Gene Polymorphism and Phenotypic Expression of COVID-19 Symptoms.
Genes - 1 Oct 2021
Yamamoto Naoki, Nishida Nao, Yamamoto Rain, Gojobori Takashi, Shimotohno Kunitada, Mizokami Masashi, Ariumi Yasuo
Abstract excerpt
The renin-angiotensin-aldosterone system (RAAS) appears to play an important role in SARS-CoV-2 infection. Polymorphisms within the genes that control this enzymatic system are candidates for elucidating the pathogenesis of COVID-19, since COVID-19 is not only a pulmonary disease but also affects many organs and systems throughout the body in multiple ways. Most striking is the fact that ACE2, one of the major...
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